Q&A+Sessions

=Q&A Sessions=

Questions to Ask:
Research Project iConS 2: Duncan, Miroslav and Chad
 * General: What specifically are you looking for in terms of environmental impacts of the drug?
 * Duncan: Is there any modification to the diffusion equation if the medium is movin
 * Chad: If a drug acts as a competitive antagonist for a specific molecule, it stops the effects of the molecule by binding to its receptor. We know that the drug gradually leaves the body, but how does this happen in terms of receptors and their corresponding molecules?

Notes on Answers:
Research Project iConS 2: Duncan, Miroslav and Chad
 * General: What specifically are you looking for in terms of environmental impacts of the drug?
 * *** Does is have environmental impacts?
 * Even if there is no evidence, there could still be an impact
 * Toxic effects on animals and plants
 * Bioaccumulation
 * All effects – metabolites, second hand smoke
 * Inverse response curve: toxic at low concentrations, but not a high concentrations
 * Toxicity of a chemical will decide whether or not a spill is a hazard
 * Look at effects of producing the drug on the environment (e.g. caffeine: deforestation)
 * All drugs are ultimately related to endorphin release in brain
 * Other ways for drugs to enter the body and how they are different
 * Cytochrome P450: enzyme that metabolizes all drugs
 * Duncan: Is there any modification to the diffusion equation if the medium is moving?
 * *** Solve in the frame of reference of the moving medium
 * Lamellar and Turbulent Flow:
 * No viscosity: lamellar (e.g. blood stream. If blood flow is turbulent then we have a problem)
 * Streamlines do cross, very unpredictable, lots of mixing
 * Convection
 * <span style="mso-bidi-font-family: "Times New Roman"; mso-fareast-font-family: "Times New Roman"; mso-fareast-language: EN-CA;">Fick’s law dP/dt is proportional to dP/dx
 * <span style="mso-bidi-font-family: "Times New Roman"; mso-fareast-font-family: "Times New Roman"; mso-fareast-language: EN-CA;">Convection – carried by the blood, for example
 * <span style="mso-bidi-font-family: "Times New Roman"; mso-fareast-font-family: "Times New Roman"; mso-fareast-language: EN-CA;">Diffusion/active transport occurs when the drug has reached the liver for example